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436th WE Heraeus Seminar
Biosensing with channels: faster, smaller, smarter

Jacobs University Bremen, Bremen, Germany

28 June - 04 July 2009

Nature has created a huge number of membrane channels acting as gates for water soluble molecules to enter the cell. Understanding gating and screening for selective substrates is a central question in biology, pharmacy and medicine. Understanding means often observation of the phenomena. In recent years physicist are attracted by these phenomena and start to benefit from this knowledge. The current task to build molecular models of the underlying physics and to test the hypothesis with adequate measurements. Nevertheless the relevance of models needs to be discussed and adopted to observations made in the bio-community. This meeting shall serve as an interdisciplinary platform: learning from biology, suggesting models and discuss the relevance. We would like to bring the different communities together to summarize the current state-of-the-art, and to elucidate future exciting developments in basic and applied science. More specifically, this school will provide research lectures on:

- physics of confined systems
- characterization of nanochannels (electrophysiology, spectroscopy)
- how to create and functionalise artificial nanometer sized channels
- how to create micrometer sized surface structure
- chemical and biological surface functionalisation
- micro and nanofluidics
- nanoelectronics
- force measurements with nanopores
- state-of-the-art structure prediction from electrophysiology
- molecular modeling
- improving the technology:
how to measure with microsecond resolution
how to automate patch-clamp or planar bilayer
how to combine fluorescence signal and electrophysiology
- how to create a biosensor

We expect about 26 invited speakers and about 70 participants in total. A few more specialized lectures on various topics will be selected from the audience. To stimulate the discussion we will arrange poster sessions.

Registration deadline is May 1st

 

Download 1st information letter

Confirmed Speakers

L. Auvray (Evry), H. Bayley (Oxford), R. Benz (Würzburg), S.M. Bezrukov (Bethesda), R. Blick (Wisconsin), M. Burger (Münster), C. Dekker (Delft), P. Hänggi (Augsburg), J. Homola (Prague), S. Howorka (London), B. Lidberg (Linköping), M. Mayer (Ann Arbor), H. Miedema (Groningen), L. Movileanu (Syracuse), J. Robertson (Gaithersburg), J.J. Schmidt (Los Angeles), G. Schütz (Linz), Z.S. Siwy (Irvine), H. Vogel (Lausanne),  A. Aksimentiev (Urbana), E. Schleiff (Frankfurt), J. Behrends (Freiburg), T. Heimburg (Copenhagen), U. Keyser (Cambridge)

Organizing Committee
Loic Auvray (University Evry, France)
Mathias Winterhalter (Jacobs University Bremen, Germany)
Ingo Köper (Max Planck Institute for Polymer Research, Germany)

SponsorFunded by the Wilhelm and Else Heraeus Stiftung